![]() ![]() These C-fibers are identical to those associated with the sensation of pain, but they are functionally distinct and only convey the itch sensation-they comprise about 5 percent of the total C-fibers in human skin. In general, pruritus involves activation of the pruriceptors of specialized nerve cells called C-fibers. Stimulation by any of these agents is typically related to inflammation, dryness or other damage to the skin, mucous membranes or conjunctiva of the eye. Prostaglandins, which are lipids that, among other functions, create the sensation of pain in spinal nerve cells.The neurotransmitters acetylcholine and serotonin.Neuropeptides, which include pain-regulating messengers released within the brain, such as endorphins.Chemicals for immune response (histamines) and pain relief (opiods).An itching sensation of the skin arises due to stimulation of pruriceptors-itch-sensing nerve endings-by mechanical, thermal or chemical mediators. Pruritus is a dominant symptom of many skin diseases and also occurs in some diseases that affect the entire body. It can alert us to harmful external agents, but can become unbearable if not treated. While it can be a nuisance, pruritus serves as an important sensory and self-protective mechanism, as do other skin sensations such as touch, pain, vibration, cold and heat. 2017 Dec 63(12):918-924.An itch, also known as pruritus, is a general sensation arising from the irritation of skin cells or nerve cells associated with the skin. Nanomedicines: A potential treatment for blood disorder diseases. Treatment of melanoma skin cancer, by stage. HIV treatment and prevention: An overview of recommendations from the IAS-USA antiretroviral guidelines panel. Treatment approach to type 2 diabetes: Past, present and future. Skin conditions: new drugs for managing skin disorders. ![]() 10 reasons your skin itches uncontrollably and how to get relief.Įbata T. New therapies are emerging that involve the use of artificial blood as a way to treat blood disorders.Īmerican Academy of Dermatology Association. Forms of treatment for blood disorders include chemotherapy, blood and bone marrow transplants, and stem cell therapy. Blood diseases: The type of blood disease will determine treatment.If it has spread, chemotherapy or radiation therapy may be needed. Surgical removal of skin cancer in the earliest stages is typically the first-line therapy. Skin cancer: Depending on the type and stage, treatments for skin cancer vary.Vital infections: Viral infections such as HIV are treated using antiretroviral therapy (ART).Diabetes, for example, is typically treated by making lifestyle changes and taking insulin and other medications to manage blood sugar levels. Since so many contribute to itching, knowing which one you have is essential. Underlying health disorders: Each underlying health disorder will be treated accordingly.For example, scabies can be treated using scabicides, which are ointments made of the medication permethrin. Parasites: Parasites need to be treated according to the type.To know the exact treatment, you must see your medical provider for a proper diagnosis of your specific condition. Skin disorders: Skin disorders are typically treated using topical emollients, hydrocortisone creams, or other prescription medications like vitamin D3 analogs and corticosteroids.Allergic reactions: Allergic reactions can be treated by avoiding the allergen or using antihistamines. ![]()
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